Cathy O'Brien (born 1957) claims to be a victim of a Central Intelligence Agency (CIA) mind control program named Project MKULTRA which involved government-sanctioned sexual abuse.  O'Brien made these claims in the TranceFormation of America (1995) and Access Denied: For Reasons of National Security (2004) which she co-authored with Mark Phillips.  O'Brien is one of many people publicly claiming to have survived government-sponsored mind control programs.  O'Brien alleges that she was abducted by the CIA as a child and forced to participate in a mind control program named Project Monarch, which is said to be a subsection of MKULTRA and Project ARTICHOKE.

O'Brien claims that, as part of Monarch, she was forced to serve as "a top-level intelligence agent and White House sex slave" for (among others) Hillary Rodham Clinton, Ronald Reagan, George H. W. Bush, Gerald Ford and Jimmy Carter with West VirginiaSenator Robert C. Byrd working as her handler for the latter part of her time in the program. She states that she remained in the program until 1988 when she was rescued by Mark Phillips, who she claims is a former CIA operative.

O'Brien alleges that her daughter Kelly (born 1980), currently a ward of the state of Tennessee, is also a victim of Monarch.

Licensed psychologist Corydon Hammond seems to confirm as credible accounts similar to O'Brien's in a speech he delivered on June 25, 1992 at at the Fourth Annual Eastern Regional Conference on Abuse and Multiple Personality entitled "Hypnosis in MPD: Ritual Abuse".

Corydon Hammond agrees with O'Brien's contention that governmental mind control programs continue to function. Critics of recovered memories such as the False Memory Syndrome Foundation are quick to add that recovered memories are not accepted without question by mental health professionals. O'Brien has stated that her knowledge of her purported abuse was gained at least partially through accessing recovered memories.

O'Brien says that she has developed dissociative identity disorder and that she has no memory of some of her activities. She also says that she has a photographic recall of the events that she suffered whilst her alternate personalities were in control.